Triptorelin Acetate

Product Introduction

Triptorelin is a gonadotrophin releasing hormone (GnRH) blocker. This means it stops messages from a part of the brain called the hypothalamus that tells the pituitary gland to produce luteinising hormone. Luteinising hormone tells the testicles to produce testosterone. So, blocking GnRH stops the testicles producing testosterone. Prostate cancer depends on testosterone to grow. So triptorelin can shrink the cancer or slow its growth. In women, it stops the ovaries from producing oestrogen. Some breast cancers depend on oestrogen to grow. Lowering the level of oestrogen can slow or stop the growth of the cancer.

Triptorelin is a GnRH agonist shown to inhibit estradiol-induced cancer cell proliferation. It is a modified (D-Trp6) LH-RH, useful in achieving medical castration in the treatment of advanced prostate cancer.